The Philips Experience Design team has designed LOTUS, a conceptual exploration of a next-generation Neonatal Intensive Care Unit (NICU). LOTUS is a suite of solutions designed to enhance the neonatal intensive care experience to help families and clinicians provide care that is personalized. Our solution features a next generation clinical informatics platform which monitors and aggregates information across all devices and systems into one easy to use interface. This interface visualizes the holistic status of the baby, which may help clinicians make critical decisions and coordinate care between teams to improve outcomes. The LOTUS solution is coupled with an adaptive healing environment that can transform from supporting the neuroprotective development of the baby, to providing a soothing and calming environment for familes, and also address workflow and care delivery needs of clinicians.